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imt-2021-0013 - Supplementary Material - Ruxolitinib, a JAK1/JAK2 selective inhibitor, ameliorates acute and chronic steroid-refractory GvHD mouse models

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posted on 08.09.2021, 10:52 by Figshare Future Science GroupFigshare Future Science Group, Eduardo Huarte, Michael Peel, Ashish Juvekar, Philip Dubé, Sarala Sarah, Lynn Stephens, Becky Stewart, Brian Long, Philip Czerniak, Julian Oliver, Paul Smith
Supplementary Figure 3. Histological characterization of hIL-15 NOG model. At termination, hIL-15 NOG mice were necropsied and tissues were observed for histological analyses using a scoring system of 0–5, with 0 being no inflammation and 5 being the highest level of inflammation.

Inflammation grades of tissues from hIL-15 NOG mice engrafted with 5 × 106 human PBMCs are presented here as mean ± SEM.

PBMC: peripheral blood mononuclear cell; SEM: standard error of the mean.

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Incyte Corporation

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