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Supplementary material. Glyco Disulfide Capped Gold Nanoparticles Synthesis: Cytotoxicity Studies, and Effects on Lung Cancer A549 Cells

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posted on 2022-01-20, 22:02 authored by Christian K. Adokoh, Frankline K. Keter, Collins Obuah, Henok H. Kinfe, Robert T. Tshikhudo, James Darkwa
Figure S1: UV-vis spectrometer of GD2 AuNP (a) Low pH 8.9-9.2 (b) High pH (12.4-12.5)
Figure S2: (d-f) TEM micrograph of AuNP GD2 with Au:L2 ratio of 1: 0.5, 1:1 and 1: 1.5 respectively at various ligand pHs. Note: d´-f´ are TEM micrograph of a-c at pH ~12 respectively
Figure S3a: Raman spectrum of gluconamidoethyl disulfide (L1)
Figure S3b: Raman spectrum of gluconamidoethyl disulfide AuNP via direct method
Figure S3c: Raman spectrum of gluconamidoethyl disulfide AuNP via ligand exchange
Figure S4: UV-vis spectrum of GD1 AuNP at different pHs.
Figure S5: General representation of substitution gold nanoparticles synthesis.
Figure S6: Preparation of glyco disulfide gold nanoparticles via photochemical irradiation method.
TEM image of the following photoirradiation of various ratios of ligands to gold are presented in the figure S7 below.
Figure S7: TEM image of GNP of (a) aggregated GD14 (b) aggregated GD15 (c) GD11 (d) GD12 (e, f) GD13.
Figure S8. Growth inhibition profile of A549 cancer cells by AuNPs GD1


DST Nanotechnology Innovation Centre at Mintek (South Africa) x no. Bio-JM-RT/2010.


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