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Supplementary figure S5. Electrochemical methods for probing DNA damage mechanisms and designing cisplatin-based combination chemotherapy

figure

posted on 2019-03-20, 15:59 authored by Zhi Li, Yael Zilberman, Qing-Bin Lu, Xiaowu (Shirley) Tang

Figure S5. GO, rGO and PEG-rGO solutions (from left to right) in PBS.

Figure S5 shows the solubility of GO, rGO and PEG-rGO after 1 hour of PBS treatment and 10 minutes of centrifugation at 14000 rpm. Both GO and rGO were insoluble after mixing with cisplatin solution, while PEG-rGO showed no aggregation.

Funding

This work was supported by an operating grant to QBL from the Canadian Institutes of Health Research (CIHR) and Discovery grants to QBL and ST from the Natural Science and Engineering Research Council of Canada (NSERC).

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Keywords

Cisplatin combination therapy DNA damage electrochemical analysis reduced graphene oxide Chemotherapy Cancer Cell Biology

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CC BY-NC-ND 4.0