supplementary figure 1.pdf (1022.45 kB)

Supplementary figure 1.pdf: A Phase I trial of talazoparib in patients with advanced hematologic malignancies

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posted on 2021-10-23, 12:03 authored by Ajay K Gopal, Rakesh Popat, Ryan J Mattison, Tobias Menne, Adrian Bloor, Terry Gaymes, Asim Khwaja, Mark Juckett, Ying Chen, Matthew J Cotter, Ghulam J Mufti

Supplementary Figure 1. Dose linearity and proportionality in plasma following multiple doses of talazoparib.

Funding

This study was sponsored by Biomarin/Medivation, which was acquired by Pfizer Inc. in September 2016 (grant number not applicable).

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A Phase I trial of talazoparib in patients with advanced hematologic malignancies

International Journal of Hematologic Oncology

Keywords

Poly(ADP-ribose) polymerase inhibition talazoparib hematologic malignancy DNA damage response BRCA1/2 mutations Hematology

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CC BY-NC-ND 4.0