Supplementary Figure 4. Silver nanoparticles induce apoptosis via NOX4-derived mitochondrial ROS and ER stress in colorectal cancer cells
Supplementary Figure 4. AgNPs induced CHOP expression in HCT116 cells dose dependently. Representative images obtained by confocal fluorescence microscopy with CHOP antibody staining. Nuclei were counter-stained with DAPI. AgNPs significantly upregulated nuclear and cytosol CHOP protein expression in HCT116 cells in a dose-dependent manner.