figure 2: Correlation of COlP-MS replicate experiments DNAse versus benzonase.
Correlation matrices of anti-HA ColP-MS to precipitate HA-tagged HMG-3 or HMG-4
plotted as a heatmap, showing the Pearson correlations between control samples
and ColP-MS experiments with either DNAse or benzonase treatments. Replicate
samples of treated Colp experiments show overall high correlation for all detected
proteins prior to calculating the significantly enriched proteins.
Thanks to Sergej Herzog for technical assistance and the CGC, funded by NIH P40OD010440, for providing strains. This work was partly sponsored by the ERC-StG-2014-637530 and the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association. All procedures conducted in this study were approved by the Berlin State Department for Health and Social (LaGeSo). The authors declare that they have no competing interests. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.