Supplementary Figure 1. Gestational Sleep Apnea Perturbations Induce Metabolic Disorders by Divergent Epigenomic Regulation.

Supplementary Figure 1. Consolidated microarray data quality control. A) Signal density plots for the consolidated microarray data. Signal distribution for each microarray is indicated by blue, green and red curves for samples belonging to the LG-SC/RA, LG-IH and LG-SF groups, respectively. Plots are based in the full probe data sets per array (n = 4,212,009 probes). B) Distribution of microarray signal intensities before (left plot) and after (right plot) quantile normalization. Signal distribution for each microarray is indicated by blue, green and red boxes for samples belonging to the LG-SC/RA, LG-IH and LG-SF groups, respectively. C) Correction of signal intensity distribution biases by quantile normalization. Signal intensity distributions according to GC content and position in the sequence before (left plots) and after (right plots) quantile normalization is shown.