Supplemental Figure 1: Prediction and characterization of diffuse large B-cell lymphoma cell-of-origin subtypes using targeted sequencing.pdf

Supplemental Figure 1: ROC curves and probability histograms for COODC model

(A) ROC curves indicating sensitivity and specificity of COODC model for ABC and GCB for GOYA training set (left) (AUC=0.9955) and GOYA held-out test set (right) (AUC=0.9309). (B) Histograms indicating count of samples within ABC probability bucket colored by Nanostring COO subtype for training set (left) and test set (right). Cutoff optimized for sensitivity and specificity indicated by vertical dark grey line, ABC-unclassified boundary indicated by blue line, and GCB-unclassified boundary indicated by orange line.