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Potential of fluorescent nanoprobe in diagnosis and treatment of Alzheimer’s disease Supplementary figures nnm-2022-0022

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posted on 2022-09-26, 10:35 authored by Jingjing Lin, Hanhan Li, Jingxuan Guo, Yue Xu, Hua Li, Jun Yan, Yuxin Wang, Haiyan Chen, Zhenwei Yuan

Alzheimer’s disease (AD) is well known for its insidious nature, slow progression and high incidence as

a neurodegenerative disease. In the past, diagnosis of AD mainly depended on analysis of a patient’s

cognitive ability and behavior. Without a unified standard for analysis methods, this is prone to produce

incorrect diagnoses. Currently, definitive diagnosis mainly relies on histopathological examination.

Because of the advantages of precision, noninvasiveness, low toxicity and high spatiotemporal resolution,

fluorescent nanoprobes are suitable for the early diagnosis of AD. This review summarizes the research

progress of different kinds of fluorescent nanoprobes for AD diagnosis and therapy in recent years and

provides an outlook on the development prospects of fluorescent nanoprobes.


the Fundamental Research Funds for the Central Universities , (Grant / Award Number: '2632022ZD01')

the 5th Phase of “333 Project” of Jiangsu Province, (Grant / Award Number: )

Natural Science Foundation Committee of China, (Grant / Award Number: ' NSFC 82001891')


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