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One-pot multicomponent synthesis of novel pyridine derivatives for antidiabetic and antiproliferative activities

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posted on 2023-07-28, 09:01 authored by Nusrat Shafiq, Nabeel Shahzad, Fatima Rida, Zaheer Ahmad, Hafiza Ayesha Nazir, Uzma Arshad, Gul Zareen, Naila Attiq, Shagufta Parveen, Maryam Rashid, Basharat Ali

Compounds MNS-1 and MNS-2 were further subjected to reflux for 2 h with the addition of ferric chloride (FeCl3) to produce MNS-3 and MNS-4, respectively (Supplementary Scheme 1).

The IR and NMR spectra of all four compounds (MNS-1–MNS-4) showed characteristic peaks that helped to identify the compounds and analyze the success of synthesis (Supplementary Figures 2–13).