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Multicomponent reactions as a privileged tool for multitarget-directed ligand strategies in Alzheimer’s disease therapy - supplementary material
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posted on 2022-10-20, 11:39 authored by Sylvain Grosjean, Irene Pacho´ n-Angona, Michella Dawra, Bernard Refouvelet, Lhassane IsmailiGraphical abstract
Table 1S. Multicomponent reactions (MCRs): reaction name and year of discovery.
Figure 1S. Hantzsch 3-component reaction (H-3CR) leading to 1,4-dihydropyridine (1,4-DHP).
Figure 2S. Biginelli 3-component reaction (B-3CR) leading to dihydropyrimidin-2-(thi)one (DHPM).
Figure 3S. Ugi 4-component reaction (U-4CR) leading to bis-amide α-acylaminocarboxamide.
