C Bonilla was supported by a grant from the Pro´ -Reitoria de Pesquisa of the University of Sa˜o Paulo (grant no. 775/2020). A Matijasevich, C Bonilla, L Schuler-Faccini and MC Scheffer received support from the National Council for Scientific and Technological Development (CNPq), Brazil. V Albuquerque Sortica is the recipient of a Senior Postdoctoral Fellowship from CNPq (104101/2020- 2). C Bonilla was a consultant on ancestry and diversity for the Global Health Equity Advisory Board of Roche/Genentech. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.