Formulation, Optimization and Validation of Floating Oral In situ Gel of Ivabradine Hydrochloride. Supplementary figures.
Supplementary Figure 1. Thermograms of pure Ivabradine hydrochloride; physical mixture (API with sodium alginate, HPMC K100 M, calcium carbonate, sodium citrate); and the optimized Ivabradine hydrochloride-loaded in situ solution.
Supplementary Figures 2, 3 & 4. Contour and response surface plots which describe relation between factors and responses