Development and characterization of a novel mucoadhesive sol-gel suppository of sumatriptan: design, optimization, in vitro, and ex vivo evaluation for rectal drug delivery. Supplementary Figures.

Supplementary Figure 1. Three-dimensional contour plots showing the effect of formulation variables (X1= ST, X2 = chitosan, and X3 = PF-127) on the drug content of hydrogels

Supplementary Figure 2. Three-dimensional contour plots showing the effect of formulation variables (X1= ST, X2 = chitosan, and X3 = PF-127) on the gel temperature of hydrogels.

Supplementary Figure 3. Three-dimensional contour plots showing the effect of formulation variables (X1= ST, X2 = chitosan, and X3 = PF-127) on the viscosity of hydrogels.

Supplementary Figure 4. Three-dimensional contour plots showing the effect of formulation variables (X1= ST, X2 = chitosan, and X3 = PF-127) on the strength of hydrogels.