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Association between genetic variants and the risk of nivolumab-induced immune-related adverse events - Supplementary Material

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posted on 2022-10-21, 08:32 authored by Chihiro Udagawa, Mari Hara Nakano, Teruhiko Yoshida, Yuichiro Ohe, Ken Kato, Taisei Mushiroda, Hitoshi Zembutsu

Supplementary figure 1 Principal component analysis plots of the study 

Supplementary figure 2: QQ plot in the GWAS

supplementary figure 3: Results from a genome-wide association study 

supplementary figure 4: Regional association plot of rs469490 associated with nivolumab-induced irAEs

Supplementary figure 5: QQ plot in the GWAS (nivolumba-induced hypothyroidism)

supplementary figure 6: Results from a genome-wide association study for nivolumba-induced hypothyroidism 

supplementary figure 7: Regional association plot of rs8023690 associated with nivolumba-induced irAEs 

Supplementary figure 8: Interaction network of nivolumba-induced irAEs associated genes generated by GeneMANIA



Funding

Japan Agency for Medical Research and Development, (Grant / Award Number: 'JP20km0405201') JSPS KAKENHI, (Grant / Award Number: 'JP20K16400')

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