Aminopyridone-linked benzimidazoles: a fragment-based drug design for the development of CDK9 inhibitors
Figure S1: Detection of apoptosis in MCF-7 cells processed with DMSO (at the left) and compound 6a (at the right)
Figure S2: MCF-7 Cell cycle analysis for compound 6a (on the left side) comparing with control (on the right side).
Table S1: Apoptotic and anti-apoptotic genes expression in MCF-7 cells for compound 6a
Table S2: Results of in silico of docking experiments of new compounds and the co-crystallized ligand (SLQ).
Spectral data All melting points were determined using Stuart digital melting point apparatus.