A novel methylated cell-free DNA marker panel to monitor treatment response in metastatic prostate cancer. Supplementary figures and tables
Supplementary Figure 1. Overview of the changes in methylation levels of each region from visit A to C for each patient.
Supplementary Figure 2. Methylation levels of each candidate region stratified by treatment type.
Supplementary Figure 3. Correlation matrices of methylation levels for all regions.
Supplementary Figure 4. Kaplan–Meier analysis of association between methylation spike status at visit B and TTCP.
Supplementary Figure 5. DNA methylation patterns of Region 1 in other tissue/cell types.
Supplementary Figure 6. DNA methylation patterns of Region 5 in other tissue/cell types.
Supplementary table 1: Patient sample collection details
Supplementary table 2: Summary of canadidated methylated regions
Supplementary table 3: Spearman correlation, Cox proportional hazards (univariate) and logistic regression analysis results
Supplementary table 4: Cox proportional hazards analysis of changes in methylation levels between visits