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nnm-2021-0022 - Supplementary Table 1

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posted on 16.09.2021, 09:10 authored by Pusch, Lennart, Brox, Regine, Scheuer, Karl, Yokosawa Tadahiro, Wu, Mingjian, Apeleo Zubiri, Benjamin, Spiecker, Erdmann, Jandt, Klaus D, Fischer, Dagmar, Hackstein, Holger

Supplementary table 1. Empty SEP and DEP do not induce relevant immune activation. MFI of the activation marker CD25, CD80 expression by monocytes, and cytokine levels in the culture supernatant following incubation of PBMCs with control DEP and control SEP. Concentrations are equivalent to the lowest and highest tested concentrations of the R848-loaded NPs, respectively. Mean ± SD of at least three independent experiments; *all replicates below lower limit of quantitation, as determined by Legendplex Software


This work was supported by the Deutsche Forschungsgemeinschaft (DFG) (GO1100/4-1), the Collaborative Research Center SFB 1278 "PolyTarget” project number 316213987 A06 (KDJ), and SFB Transregio 94 “Innate Immunity of the lung” project A02 (HH). We gratefully acknowledge the additional support of the Deutsche Forschungsgemeinschaft (DFG), grant references INST 275/389-1 FUGG; AOBJ: 640980 (KDJ).