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Variation analysis of SARS-CoV-2 complete sequences from Iran: Supplementary data

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posted on 2022-10-22, 11:25 authored by Jale Moradi, Parnia Moradi, Amir H Alvandi, Ramin Abiri, Mohsen Moghoofei

Aim: SARS-CoV-2 is an emerging coronavirus that was discovered in China and rapidly spread throughout

the world. The authors looked at nucleotide and amino acid variations in SARS-CoV-2 genomes, as well

as phylogenetic and evolutionary events in viral genomes, in Iran. Materials & methods: All SARS-CoV-

2 sequences that were publicly released between the start of the pandemic and 15 October 2021 were

included. Results: Themajority of mutations were found in vaccine target proteins, Spike and Nucleocapsid

proteins, and nonstructural proteins. The majority of the viruses that circulated in the early stages of the

pandemic belonged to the B.4 lineage. Conclusion: We discovered the prevalence of viral populations

in Iran. As a result, tracking the virus’s variation in Iran and comparing it with a variety of nearby

neighborhoods may reveal a pattern for future variant introductions.

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