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The societal impact of early intensified treatment in patients with type 2 diabetes mellitus: Supplementary material

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posted on 2022-09-28, 16:11 authored by Foteini Tsotra, Mathias Kappel, Platon Peristeris, Giovanni Bader, Eva Levi, Nicola Lister, Ankur Malhotra, Dennis A Ostwald
<p>Aim: The current study estimates the societal impact of early intensified treatment compared with initial</p> <p>monotherapy with subsequent treatment intensification in newly diagnosed adults with type 2 diabetes</p> <p>mellitus in Mexico. Methods: An individual patient-level simulation and a static cohort model were</p> <p>employed to simulate the treatment pathway and the probability of experiencing complications of</p> <p>diabetes. The avoided number of events was translated into avoided productivity losses, which were</p> <p>monetized using wages. Results: Patients on early intensified treatment experienced approximately</p> <p>13,000 fewer complication events over 10 years. This was translated into a societal impact of $54 million</p> <p>(USD). Conclusion: Early treatment intensification is likely to be of particular benefit to health outcomes</p> <p>and productivity losses.</p>

Funding

This work was funded by Novartis Pharma AG. F Tsotra, P Peristeris, E Levi and M Kappel are employees of WifOR institute, an independent economic research institute in Darmstadt, DA Ostwald is the CEO of WifOR institute. G Bader, A Malhotra and N Lister are employees of Novartis.

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