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Synthesis and in vitro studies for structure-based design of novel chalcones as antitubercular agents targeting InhA - SUPPLEMENTARY FILES FOR TABLES.docx

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posted on 12.05.2022, 09:13 by Loganathan S Dhivya, Balappaudayar R Pradeepa, Sabarathinam Sarvesh

 Table 1. Structure of the prepared chalcones 

  

Table 2. Synthesis of Chalcone Derivatives

  

Table 3. Docking Score and Interactions of Designed Chalcone Derivatives

  

Table 4. Physicochemical Properties of the designed Inhibitors

  

Table 5. Toxicity Profile of the designed Chalcone Derivatives

  

Table 6. In-silico Pharmacokinetic Profile of the designed Chalcone Derivatives

  

Table 7. Bioactivity Score and Medicinal Chemistry of the designed Chalcone Derivatives

  

Table 8. Antimycobacterial activity of Chalcone Derivatives

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