Supplementary Table.docx (13.49 kB)

Supplementary Table: Simultaneous estimation of ZY-19489 and its active metabolite, ZY-20486 in human plasma using LC-MS/MS; a novel anti-malarial compound

dataset

posted on 2021-11-15, 15:52 authored by Ashok M Ghoghari, Harilal V Patel, Nisarg N Nayak, Tariq H Mansuri, Soma M Pillai, Mukul R. Jain, Hardik B Patel, Kevin Kansagra, Ilaria Di Resta, Jörg Möhrle, Deven V Parmar

Details the percent recovery of ZY-19489 and ZY-20486 using different extraction methods from human plasma compared to neat sample.

Funding

This study was funded by Cadila Healthcare Limited, based at Ahmedabad, Gujarat, India. The clinical phase of study (ACTRN12619000127101) was performed at Q-Pharm, Australia and Bioanalytical phase of the study was conducted at Bioanalytical Laboratory, Zydus Research Centre, Cadila Healthcare Limited, Ahmedabad, Gujarat, India. Zydus Research Centre (ZRC) communication number: 668. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

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Keywords

ZY-19489 ZY-20486 LC-MS/MS method validation human plasma Analytical Biochemistry

Licence

CC BY-NC-ND 4.0