Long-term effects of COVID-19 on lungs and the clinical relevance: a 6-month prospective cohort study Supplementary Table 1
Background: We aimed to explore the prevalence of prolonged symptoms, pulmonary impairments and
residual disease on chest tomography (CT) in COVID-19 patients at 6 months after acute illness. Methods: In
this prospective, single-center study, hospitalized patients with radiologically and laboratory-confirmed
COVID-19 were included. Results: A high proportion of the 116 patients reported persistent symptoms
(n = 54; 46.6%). On follow-up CT, 33 patients (28.4%) demonstrated residual disease. Multivariate analyses
revealed that only neutrophil-to-lymphocyte ratio was an independent predictor for residual disease.
Conclusion: Hospitalized patients with mild/moderate COVID-19 still had persistent symptoms and were
prone to develop long-term pulmonary sequelae on chest CT. However, it did not have a significant effect
on long-term pulmonary functions.