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Supplementary Table 1: SUMOylation of the chromodomain factor MRG-1 in C. elegans affects chromatin-regulatory dynamics

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posted on 2022-06-14, 07:17 authored by Gülkiz Baytek, Alexander Blumenfeld, Funda Gerceker Demirel, Selman Bulut, Oliver Popp, Philipp Mertins, Baris TursunBaris Tursun

 Supplemental table 1.  Source data for MRG-1::3xHA co-IP mass spectrometry. Anti-HA co-immunoprecipitations (co-IPs) targeting MRG-1::3xHA with subsequent LFQ mass spectrometry (IP-MS) to determine MRG-1 protein interactions. Wildtype (N2) with no HA tag was used as a negative control to eliminate background and mrg-1::3xHA (CRISPR/Cas9 generated) strain was used to identify MRG-1-interacting proteins. Enrichment of MRG-1 and its interaction partners between the IP and the control samples and their corresponding adjusted p value are listed. Statistics: t-test, adjusted P-value of 0.05 as false discovery rate cut-off. 

Funding

Thanks to Tim Wolfram and Sergej Herzog for technical assistance and the CGC, funded by NIH P40OD010440, for providing strains. This work was partly sponsored by the ERC-StG-2014-637530 and the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript.

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