Supplementary Material: Body composition and inflammation impact in non-small cell lung cancer patients treated by first line immunotherapy

Table 1 Supplementary Material. Study with mono-immunotherapy in first line in NSCLC: CheckMate 026 and Keynote 024

Table 2 Supplementary Material. Variation of blood exams and CT scan values from baseline to first re-staging°

Table 3 Supplementary Material. Correlation between different characteristics of patients

Table 4 Supplementary Material. Overall Survival Univariate analysis with baseline WBC, albumin, CRP and NLR considered as continuous variable and Multivariate analysis with WBC, albumin, SMI and VSR as continuous variables

Figure 1 Supplementary Material. Kaplan-Meier Overall Survival curves according to SFI and CRP variation

Figure 2 Supplementary Material. Selected CT scan parameters (3 for muscle mass and 3 for adipose tissue) in relation with response, comparing values at baseline and first re-staging

Figure 3 Supplementary Material: ROC curves and Kaplan Meier (KM) Overall Survival curves according to selected parameters. A: white blood cell (WBC), B: albumin, C: C-reactive protein (CRP). 1: ROC curves; 2: KM curves divided with cut-offs derived from ROC curves, 3: KM curves divided with median, 4: KM curves divided with selected cut-offs (upper normal limit (UNL) or low normal limit (LNL).

Figure 4 Supplementary Material: ROC curves and Kaplan Meier (KM) Overall Survival curves according to selected parameters. D: Neutrophil-to-lymphocyte ratio (NLR), E: Skeletal Muscle Index (SMI), F: Advance lung cancer inflammation index (ALI score). 1: ROC curves; 2: KM curves divided with cut-offs derived from ROC curves, 3: KM curves divided with median, 4: KM curves divided with selected cut-offs derived from literature (c.o.).