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Long-term pharmacokinetic and pharmacological evaluations of a novel indole-benzazepinone derivative on obese T2DM - Supplementary material

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posted on 2022-09-15, 09:29 authored by Youde Wang, Shuai Li, Zhiwei Yan, Yachun Guo, Dongxin Yang, Liying Zhang

 Table 1. Effects of the tested compounds on insulin in obese hyperglycemic DIO mouse model 

 Fig. 1 Effects of the tested compounds on food consumption in obese hyperglycemic DIO mouse model induced by HFD 

 Table 2. Effects of the continuous administration of the test compounds on the biochemical parameters of obese hyperglycemic DIO mouse model induced by HFD 

 Table 3. Effects of the tested compounds on liver in obese hyperglycemic DIO mouse model induced by HFD 

 Fig. 2 Effects of the tested compounds on liver organs coefficients in obese hyperglycemic DIO mouse model induced by HFD 

Funding

Natural Science Foundation of Hebei Province, (Grant / Award Number: 'No. H2021406034') Open project supported by Hebei Province Key Laboratory of Traditional Chinese Medicine Research and Development, (Grant / Award Number: 'No. ZYKF202008') Technology Innovation Guidance Project-Science and Technology Work Conference Fund of Hebei Provincial Department of Science and Technology, (Grant / Award Number: )

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