Future Science Group
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Layer-by-layer self-assembled emerging systems for nanosized drug delivery - supplementary dataset

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posted on 2023-01-16, 11:22 authored by Nejla Cini, Ferah Calisir

New frontiers in the development of stimuli-responsive surfaces that offer switchable properties according

to the end-use application have added a new dimension to the design of drug-delivery systems (DDS). In

this respect, layer-by-layer (LbL) self-assembled technologies have attracted interest in nano-DDS (NDDS)

design due to the advantage of encapsulating different drug types either individually or in multiple

formulations as an easy-to-apply and cost-effective strategy. LbL-based microcapsules and core-shell

structures in the form of polyelectrolyte multilayers (PEMs) have been proposed as versatile vehicles for

NDDS over the last quarter. This review aims to provide a global view of LbL-PEMs used as templates in

NDDS for the last 5 years with an emphasis on emerging drug loading and release strategies.