Future Science Group
Browse
1/1
18 files

Improving the antimicrobial activity of old antibacterial drug mafenide: Schiff bases and their bioactivity targeting resistant pathogens - Supplementary Material

dataset
posted on 2023-03-09, 09:50 authored by Martin Kr ´atk´y, Klara Konecna, Adela Simkova, Ondrej Jandourek, Jana Maixnerova, Jirina Stolarıkov, Marcela Vejsová, Barbora Voxová, Frantisek Trejtnar, Jarmila Vinsov

1H & 13C NMR spectra 


Figure S1. Modification of salicylidene and heteroarylidene derivatives

Figure S2. Time-dependent interaction of 4d with VRSA at MIC and sub-MIC values

Figure S3. Time-dependent interaction of 4d with MRSA at MIC and sub-MIC values

  

Table S1. List of strains from the genus Staphylococcus and Enterococcus with their susceptibility/resistance profile used for extended study of antibacterial action within selected mafenide derivatives

  

Table S2. Activity of active mafenide derivatives 1-4 against Gram-negative bacteria

  

Table S3. Activity of the mafenide derivatives against drug-resistant TB strains


Funding

Univerzita Karlova v Praze, (Grant / Award Number: 'SVV 260 547') Grantová Agentura České Republiky, (Grant / Award Number: '20-19638Y') Ministerstvo Zdravotnictví Ceské Republiky, (Grant / Award Number: 'NU21-05-00482') European Commission, (Grant / Award Number: 'National Institute of virology and bacteriology [P')

History

Usage metrics

    Future Medicinal Chemistry

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC