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Identification of dual-targeted Mycobacterium tuberculosis aminoacyl-tRNA synthetase inhibitors using machine learning - Supplementary Material

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posted on 2022-07-25, 10:38 authored by Galyna P. Volynets, Mariia O. Usenko, Olga I Gudzera, Segiy A Starosyla, Anatoliy O Balanda, Anatolii R Syniugin, Oksana B. Gorbatiuk, Andrii O Prykhod’ko, Volodymyr G. Bdzhola, Sergiy M. Yarmoluk, Michael A. Tukalo

 Table S1. Structures and in vitro inhibitory activity (%) of compounds at the concentration of 100 µM toward Mycobacterium tuberculosis methionyl-tRNA synthetase (MetRS)  


  

Table S2. Structures and in vitro inhibitory activity (%) of compounds at the concentration of 100 µM toward Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) 

Funding

the National Research Foundation of Ukraine , (Grant / Award Number: '0120U104850')

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