Future Science Group
Download file
Download file
2 files

Highlighting the role of immune responses,cell death and the nervous system in acuterotavirus infection using weighted geneco-expression network analysis: supplementary tables

posted on 2023-09-05, 17:42 authored by Saeed Samadizade, Ali Vaez, Zahra Jamalpoor, Alireza Tahamtan

Aim: Identifying genes and pathways involved in various stages of rotavirus infection could facilitate

the mapping of the interactions between the virus and host. Materials & methods: Weighted gene

co-expression network analysis (WGCNA) was employed to construct a co-expression network of genes

identified by microarray analysis from samples from children with acute rotavirus infection. Results: Two

specific modules were most related to rotavirus infection. The analysis of differentially expressed genes

(DEGs) disclosed 393 DEGs between normal and infected individuals. Eighteen novel genes were shared

between the modules. Conclusion: TheWGCNArevealed novel modules, co-expressed genes and pathways

involved in immune responses, cell death/degradation and the nervous system in acute rotavirus infection.