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Green solvent-free synthesis of new N-heterocycle-L-ascorbic acid hybrids and their antiproliferative evaluation - Supplementary Information.docx

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posted on 2022-07-06, 08:08 authored by Andrea Bistrovi´c Popov, Andrijana Meˇsˇci´c Macan, Silvio Jakopec, Helena Prpi´c, Anja Harej Hrka´c, Sandra Kraljevi´c Paveli´c, Silvana Rai´c-Mali´c

General procedure for the synthesis of N-propargylated bases

1H and 13C NMR chemical shifts for compounds 15a-23a and 15b-23b

. 1H and 13C NMR spectra of compounds 15a-23a and 15b-23b

ROESY NMR spectrum of compound 15b.

Funding

Hrvatska Zaklada za Znanost, (Grant / Award Number: 'HRZZ-IP-2018-01-4682')

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Keywords

1,2,3-triazole antitumor activity CuAAC green chemistry L-ascorbic acid mechanochemistry nucleobase purine pyrimidine

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CC BY-NC-ND 4.0

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