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Gold-, silver- and magnesium-doped zinc oxide nanoparticles prevents the formation of and eradicates bacterial biofilms - supplementary tables

posted on 2023-05-31, 10:22 authored by Erlen Cruz Jorge, Nicolas Navarro Martınez, Marıa Jose Gonzalez, Sofıa V Sanchez, Luciana Robino, Javier O Morales, Paola Scavone

Aim: This work aimed to synthesize magnesium-doped zinc oxide, silver and gold nanoparticles (Nps) and

to evaluate their potential to prevent and eradicate Escherichia coli, Proteus mirabilis, Staphylococcus

aureus, Acinetobacter baumannii and Pseudomonas aeruginosa biofilms. Materials & methods: The Nps

were synthesized by precipitation and metallic reduction techniques. Physicochemical and biological

characterization of Nps was performed. Results: All the Nps tested were able to inhibit the formation of E.

coli, P. mirabilis, S. aureus and A. baumannii biofilms. The effects on the eradication of preformed biofilms

were variable, although all the Nps tested were able to eradicate A. baumannii biofilms. Conclusion: The

observed effects make the Nps suitable for coating surfaces and/or antibiotic carriers with medical interest.


Comisión Sectorial de Investigación Científica, (Grant / Award Number: 'CSIC I+D')

Chilean National Agency for Research and Development (ANID), (Grant / Award Number: 'ANID/PIA/ACT192144','FONDAP Project 15130011','FONDEQUIP EQM 160157','FONDEQUIP EQM 170111' 'National Doctoral Scholarship 21201831','Regular FONDECYT Project 1181689')

Biotechnology in Latin America and the Caribbean (UNU-BIOLAC), (Grant / Award Number: 'Fellowship 2019','Fellowship 2022')

National Research and Innovation Agency of Uruguay (ANII), (Grant / Award Number: 'National Doctoral Scholarship POS_NAC_D_2020_1_164')