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Epigenetic signature of exposure to maternal Trypanosoma cruzi infection in cord blood cells from uninfected newborns. Supplementary data.

posted on 2022-08-30, 05:59 authored by Eric Dumonteil, Carine Truyens, Claudia Herrera, Emily W. Harville, María Luisa Cafferata, Jackeline Alger, Pierre Buekens, Hans Desale


Supplementary Table S1. Gene function and ontogeny.


Supplementary Figure 1. Methylation level of differentially methylated CpG sites. After adjustment over all umbilical cord cell types, 12 CpGs yielded experiment-wide  level of significance when combining the effects of all cell types (A-L). Data are  presented as box plots of the methylation levels determined as the tensor() function in  TCA for Unexposed ad Exposed groups (See text for additional methods). Ten sites  were hypomethylated, and two were hypermethylated. Sites in A-I were detected in B  cells and sites in J-L in CD4+ T cells.