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EPI-2021-0192 Supplementary File

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posted on 29.09.2021, 14:14 by Markos Tesfaye, Suvo Chatterjee, Xuehuo Zeng, Paule V. Joseph, Fasil Tekola-Ayele

Table S1. Latent Class Trajectory Model Output for Perceived Stress Scores and Depression Symptom Scores among pregnant women of the Fetal Growth Studies

Table S2. Sensitivity analysis of top significant placental CpGs at delivery associated with antenatal Table S3. Enriched networks of nearest genes of top 100 CpGs associated with depression at baseline visit

Table S4. Enriched networks of nearest genes of top 100 CpGs associated with depression during visit 1

Table S5. Enriched networks of nearest genes of top 100 CpGs associated with depression during visit 2

Table S6. Enriched networks of nearest genes of top 100 CpGs associated with depression during visit 3

Table S7. Enriched networks of nearest genes of top 100 CpGs associated with depression during visit 4

Table S8. Enriched networks of nearest genes of top 100 CpGs associated with depression during visit 5

Table S9. Enriched networks of nearest genes of top 100 CpGs associated with perceived stress during baseline visit

Table S10. Enriched networks of nearest genes of top 100 CpGs associated with perceived stress during visit 1

Table S11. Enriched networks of nearest genes of top 100 CpGs associated with perceived stress during visit 2

Table S12. Enriched networks of nearest genes of top 100 CpGs associated with perceived stress during visit 3

Table S13. Enriched networks of nearest genes of top 100 CpGs associated with perceived stress during visit 4

Table S14. Enriched networks of nearest genes of top 100 CpGs associated with perceived stress during visit 5

Figure S1. Inflation corrected Q-Q plots for EWAS of depression during pregnancy at six assessment time-points.

Figure S2. Inflation corrected Q-Q plots for EWAS of perceived stress during pregnancy at six assessment time-points.

Figure S3. Manhattan plots showing the distribution of placental CpGs and their association with class trajectories of maternal depression and perceived stress with the BACON adjusted lambda values

Figure S4. Expression levels in various tissues of selected genes annotated to depression-associated CpGs in placenta [proteinatlas.org]

Funding

Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institutes of Health, including American Recovery and Reinvestment Act

History