Design and synthesis of selective FLT3 inhibitors via exploration of back pocket II - Supplementary material
Representative off-target/selective ligands
1H NMR and 13C NMR Spectra of Title Compounds
Table 1. Sequence identity (%, ATP binding site) between FLT3 and 328 other structural kinases that are gradually color-coded from green to orange to red. The ATP sites were defined according to KLIFS .
Table 2: Number of selective FLT3 inhibitors against 269 other kinases